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Year Number of Results
2018 1
2021 3
2022 4
2023 3
2024 0

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11 results

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Page 1
Genome expansion by a CRISPR trimmer-integrase.
Wang JY, Tuck OT, Skopintsev P, Soczek KM, Li G, Al-Shayeb B, Zhou J, Doudna JA. Wang JY, et al. Among authors: soczek km. Nature. 2023 Jun;618(7966):855-861. doi: 10.1038/s41586-023-06178-2. Epub 2023 Jun 14. Nature. 2023. PMID: 37316664 Free PMC article.
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, Doudna JA. Al-Shayeb B, et al. Among authors: soczek km. Cell. 2022 Nov 23;185(24):4574-4586.e16. doi: 10.1016/j.cell.2022.10.020. Cell. 2022. PMID: 36423580 Free article.
Rapid assessment of SARS-CoV-2-evolved variants using virus-like particles.
Syed AM, Taha TY, Tabata T, Chen IP, Ciling A, Khalid MM, Sreekumar B, Chen PY, Hayashi JM, Soczek KM, Ott M, Doudna JA. Syed AM, et al. Among authors: soczek km. Science. 2021 Dec 24;374(6575):1626-1632. doi: 10.1126/science.abl6184. Epub 2021 Nov 4. Science. 2021. PMID: 34735219 Free PMC article.
DNA interference states of the hypercompact CRISPR-CasΦ effector.
Pausch P, Soczek KM, Herbst DA, Tsuchida CA, Al-Shayeb B, Banfield JF, Nogales E, Doudna JA. Pausch P, et al. Among authors: soczek km. Nat Struct Mol Biol. 2021 Aug;28(8):652-661. doi: 10.1038/s41594-021-00632-3. Epub 2021 Aug 11. Nat Struct Mol Biol. 2021. PMID: 34381246 Free PMC article.
Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs.
Stahl EC, Sabo JK, Kang MH, Allen R, Applegate E, Kim SE, Kwon Y, Seth A, Lemus N, Salinas-Rios V, Soczek KM, Trinidad M, Vo LT, Jeans C, Wozniak A, Morris T, Kimberlin A, Foti T, Savage DF, Doudna JA. Stahl EC, et al. Among authors: soczek km. Mol Ther. 2023 Aug 2;31(8):2422-2438. doi: 10.1016/j.ymthe.2023.06.019. Epub 2023 Jul 4. Mol Ther. 2023. PMID: 37403358 Free article.
CRISPR-Cas9 bends and twists DNA to read its sequence.
Cofsky JC, Soczek KM, Knott GJ, Nogales E, Doudna JA. Cofsky JC, et al. Among authors: soczek km. Nat Struct Mol Biol. 2022 Apr;29(4):395-402. doi: 10.1038/s41594-022-00756-0. Epub 2022 Apr 14. Nat Struct Mol Biol. 2022. PMID: 35422516 Free PMC article.
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9.
Eggers AR, Chen K, Soczek KM, Tuck OT, Doherty EE, Thornton BW, Xu B, Trinidad MI, Doudna JA. Eggers AR, et al. Among authors: soczek km. bioRxiv [Preprint]. 2023 Dec 15:2023.12.14.571777. doi: 10.1101/2023.12.14.571777. bioRxiv. 2023. PMID: 38168238 Free PMC article. Preprint.
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
Amen AM, Fellmann C, Soczek KM, Ren SM, Lew RJ, Knott GJ, Park JE, McKinney AM, Mancini A, Doudna JA, Costello JF. Amen AM, et al. Among authors: soczek km. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2008772118. doi: 10.1073/pnas.2008772118. Proc Natl Acad Sci U S A. 2021. PMID: 33758097 Free PMC article.
11 results